This is even true between different specimens from the same flush, presenting a real challenge when calculating how many mushrooms to take. Moreover, because they are a natural product, the amount of psilocybin in each mushroom or truffle can vary significantly. Anecdotal reports also suggest that, in general, magic mushrooms are more potent than magic truffles. cyanescens, are considered more potent than P. There are many different psilocybin mushrooms, and some are more potent than others.įor example, certain Psilocybe species, including P. However, these figures are highly dependent on the type of mushroom involved. The latter publication suggests that 1–4g of dried mushrooms constitutes a dose. This aligns with information from the Oregon Psilocybin Advisory Board Rapid Evidence Review and Recommendations. The review suggests that 10–50g of fresh mushrooms or 1–5g of dried mushrooms is roughly equivalent to 10–50mg of psilocybin. Without highly specialized extraction and chromatography equipment, it is impossible to know for sure. Some also contain other psychoactive compounds, such as psilocin and baeocystin.Īccording to a 2021 review, dried mushrooms usually contain approximately 0.1–0.2% psilocybin, although this figure can vary greatly. Dosing is far more complex because different mushrooms produce varying amounts of psilocybin. While there is plenty of research into psilocybin dosage, mushrooms are another matter. For example, there were no additional effects in heavier or lighter participants who took similar amounts of psilocybin. The results suggested that there was no significant difference in subjective effects between the weight-adjusted and fixed doses.
It compared participants who took a weight-adjusted dose of 20 or 30mg of psilocybin per 70kg with those who took a fixed amount of approximately 25mg. However, while bodyweight appears to play a role in dosing, it may not be as crucial as initially thought.Ī 2021 publication analyzed data from ten previous studies. Other research suggests that doses of 45–315mcg/kg may be effective, with the risk of adverse reactions increasing at doses over 420mcg/kg. Although higher doses correlated more strongly with lasting positive outcomes, they also increased the risk of adverse reactions, including anxiety and fear. Most trials involve doses of 20–30mg per 70kg of weight, with doses over 25mg considered relatively high.Īccording to a 2012 study, doses as low as 5mg/70kg produced subjective effects in some participants.
Dosage and Body Weightīodyweight is often considered one of the most critical factors in determining an appropriate psilocybin dosage. Read on for a summary of the latest research on mushroom and psilocybin dosing and other influential factors. While our magic mushroom dosage calculator provides a rough estimate, there are many other things to consider.
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